Source — JAMA
Importance Health care professionals commonly recommend increased water consumption, typically to 8 cups per day, as part of a weight-reducing diet. However, this recommendation is based on limited evidence and virtually no experimental data from the pediatric population.
Effect of Alternate-Day Fasting on Weight Loss, Weight Maintenance, and Cardioprotection Among Metabolically Healthy Obese Adults
Source — JAMA
Importance Alternate-day fasting has become increasingly popular, yet, to date, no long-term randomized clinical trials have evaluated its efficacy.
Source — JAMA
Importance Umbilical hernia repair is one of the most commonly performed general surgical procedures. However, there is little consensus about the factors that lead to umbilical hernia recurrence.
Importance: The variability and durability of improvements in pain and physical function following Roux-en-Y gastric bypass (RYGB) or laparoscopic adjustable gastric banding (LAGB) are not well described.
Since the end of the Civil War until the late 20th century, lifespan increased rapidly in the United States, a tremendous public health triumph brought about by a more dependable food supply, improved sanitation, and advances in medical care. In 1850, life expectancy among whites was an estimated 38 years for men and 40 years for women.
Contestants lost hundreds of pounds during Season 8 of the Biggest Loser, but gained the weight back. A study of their struggles helps explain why so many people fail to keep off the weight they lose.
Almost everyone who has ever dieted knows how hard it is to keep the weight off. And almost everyone, including many scientists, has wondered what works.
In recent news, a California judge ruled that Kaiser Foundation cannot routinely deny coverage for skin excess procedures by classifying them as cosmetic in nature. The class action lawsuit, started by Wendy Gallimore of Alameda County in 2012, argued that Kaiser violated California law by refusing to cover procedures designed to remove excessive skin after surgical weight loss. The lawsuit and updates are in the Kaiser Plastic Surgery Class Action Lawsuit (Updated) article.
Previous studies comparing early laparoscopic cholecystectomy (ELC) with delayed laparoscopic cholecystectomy (DLC) for acute cholecystitis were incomplete. A meta‐analysis was undertaken to compare the cost‐ effectiveness, quality of life, safety and effectiveness of ELC versus DLC.
Wabitsch et al. (Jan. 1 issue) 1 highlight how biologically inactive leptin from a mutation in the leptin gene (p.D100Y) led to early-onset extreme obesity in a 2-year-old boy, a finding that paralleled a murine model encoding mutated leptin (p.V145E). The authors cite studies that characterize leptin as an adipocyte-derived hormone reflecting body energy status and functioning as a satiety signal in the hypothalamus. Hence, the mechanism of obesity is ascribed purely to that resulting from hyperphagia and consequently high energy intake.